Seconde Peau by Biologique Recherche: A Professional Protocol for Post-Treatment Recovery and Regenerative Skincare

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*Sponsored post: SkinKo*  

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Biologique Recherche’s Seconde Peau (Second Skin) treatment brings medical-grade science into the hands of aesthetic professionals. Drawing on techniques originally developed for burn care, this advanced protocol uses sterile electrospun hyaluronic acid technology to visibly lift, plump, and support skin regeneration.  

What is Seconde Peau? 

At the heart of the treatment are electrospun hyaluronic acid patches and a high-performance regenerating serum. The patches contain 80% medical-grade hyaluronic acid with a very low molecular weight (77 kDa), allowing deeper skin penetration and delivering up to 40 times the concentration found in conventional skincare. 

Originally developed from technologies used in wound healing, Seconde Peau is particularly effective in: 

• Reducing the appearance of wrinkles and fine lines 

• Plumping and firming facial contours 

• Accelerating epidermal renewal 

• Enhancing skin density and hydration 

• Restoring luminosity to fatigued or dull skin 

It’s recommended for those with compromised, ageing, or post-procedure skin, including individuals not yet ready for injectables but seeking visible results. 

A sterile, professional-only treatment 

This is not a take-home or retail product. Seconde Peau is administered by trained professionals in a clinical or salon environment, ensuring strict hygiene and sterile application. The patches are individually packaged and applied using sterile tweezers to avoid contamination, aligning the treatment with medical-grade safety standards. 

How the treatment works 

Seconde Peau fits seamlessly into a professional aesthetic offering, whether as a standalone treatment performed in a weekly series or as a supportive treatment after procedures such as microneedling, laser, or injectables.  

While the treatment visibly improves skin tone, firmness, and hydration on its own, it’s equally effective at reducing downtime and promoting healing when used post-procedure. 

In these cases, the application protocol may differ slightly depending on the procedure performed. For best results, practitioners should consult Biologique Recherche’s training team for tailored guidance on advanced protocols. 

Standalone protocol: Step-by-step 

When performed as a standalone treatment, Seconde Peau follows a structured three-step process, typically lasting around 10 minutes after cleansing and preparation: 

Step 1: Prepare 

• The skin is thoroughly cleansed and exfoliated according to the Biologique Recherche method, customised to the client. 

Step 2: Application 

• Seconde Peau Serum is applied to the target zones. 

• Hyaluronic acid patches are applied with the smooth side against the skin. 

• The honeycombed backing is moistened and gently removed, followed by additional serum and a sequence of massage movements including skin rolling, Jacquet-Leroy pinching, and smoothing. 

Step 3: Final massage 

• The remaining serum is massaged into the face until fully absorbed. 

• This process can be repeated across multiple areas, depending on the skin’s needs. 

Clinically inspired results 

Clinical observations show a 70% acceleration in epidermal healing when compared to untreated areas, making this an excellent adjunct to procedures like microneedling, laser, or filler treatments. 

Patients report an immediate visible lifting effect, with improved tone and comfort over the days that follow.  

Regular use (in a series of four weekly treatments) supports longer-term improvements in dermal density and resilience. 

Key ingredients and skin benefits 

The treatment works across multiple skin actions, thanks to its thoughtfully formulated serum and patch complex: 

• Hyaluronic acid (low and high molecular weight) – deep hydration, wrinkle reduction, and collagen stimulation 

• Marine exopolysaccharides – firming and lifting from sea-based biotech ingredients 

• Damask rose extract – smooths and revitalises 

• Centella asiatica and madecassoside – calms inflammation, reduces sensitivity 

• Vitamin B5 and arnica – soothes and relieves skin discomfort 

• Chlorella sorokiniana (microalgae) – boosts skin oxygenation and resilience 

• Dandelion fructans – helps detoxify and shield against environmental aggressors 

Who is it for? 

Seconde Peau is ideal for clients with: 

• Ageing, wrinkled, or thin skin 

• Post-procedure skin in need of accelerated healing 

• Sensitive, intolerant, or asphyxiated skin 

• Thickened or keratinised skin in need of a smooth, fresh finish 

It is also well-suited for professionals looking to offer non-injectable yet visibly corrective results, or to complement more invasive treatments with a restorative follow-up protocol. 

The final layer 

Biologique Recherche’s Seconde Peau is more than just a treatment – it’s a regenerative skin therapy drawing from the best of clinical science. Its sterile application, medical-grade ingredients, and visible results position it as a unique offering for practices and salons seeking to deliver both comfort and correction.  

In a world increasingly drawn to natural, evidence-based results, Seconde Peau stands out for all the right reasons. 

Contact Biologique Recherche 

SkinKo is the exclusive distributor of Biologique Recherche in Southern Africa.  

For more information on becoming a stockist or offering Biologique Recherche professional treatments, visit www.skinko.co.za, email info@skinko.co.za, or call +27 66 449 8415.

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