*Sponsored post: FILLMED South Africa*
Ageing isn’t just about lines on the surface — it begins much deeper. One of the most overlooked features of youthful skin is the internal architecture that holds everything up: the extracellular matrix. When that supporting “mesh” weakens, the skin sags, contours soften, and firmness fades. ARCHITECH-PRO CREAM, formulated by FILLMED, brings an advanced regenerative approach to this challenge, using clinically referenced actives designed to help rebuild the skin’s internal matrix from the inside out — all while smoothing, refining and re-supporting the complexion.
Rebuilding the Skin Matrix: What Ageing Really Looks Like
Beneath the epidermis sits a structured network known as the extracellular matrix (ECM). This framework is rich in four key youth-defining proteins:
- Collagen (firmness and structure)
- Laminin (epidermal-dermal anchoring)
- Elastin (spring-like flexibility)
- Fibrillin (elastin scaffolding)
With age, sun exposure, environmental stress and enzymatic activity, these proteins naturally decline — collagen alone drops by as much as 75% between our 20s and 80s.
The result? Softened contours, loss of elasticity, sagging along the jawline, diminished definition, and thinning epidermal support.
ARCHITECH-PRO CREAM is formulated to specifically target these internal markers of structural ageing: the proteins responsible for lift, bounce, integrity and youthful firmness.
Designed to Act on C.L.E.F Proteins
ARCHITECH-PRO Cream works on the four core matrix proteins:
- Collagen
- Laminin
- Elastin
- Fibrillin
In internal testing, the formula demonstrated stimulation of all four proteins, with notable increases in fibroblast activity — the skin’s essential matrix-producing cells.
The Formula: SI-HYAL® + Pro-Matrix Actives
The cream centres around a scientifically referenced blend of ingredients, including:
SI-HYAL® Complex (7.45%)
A proprietary mix of two molecular weights of hyaluronic acid engineered with organic silanol and cell-targeting technology. This vectoring function is designed to direct the actives deeper into targeted skin layers for enhanced biological activity.
Mannose-6P (4%)
A biomimetic energy-restoring saccharide that supports cell vitality, matrix remodelling and dermal-epidermal junction cohesion.
Phyto-Silybin (0.8%)
A botanical antioxidant from milk thistle, positioned as a gentler alternative to retinoids. It encourages skin renewal and supports restoration of structural proteins.
Biolipids (1%)
Ceramides, cholesterol and fatty acids to reinforce barrier integrity, calm sensitivity and improve moisture retention.
Clinical Outcomes Reported
Over 56 days of use (applied twice daily), internal study results showed improvements across multiple markers of structural ageing:
- Firmness: +13%
- Elasticity: +12%
- Lift effect: +11%
- Smoothness: +11%
- Wrinkles: −7%
- Roughness: −15%
Additional skin structure markers were also evaluated, including epidermal thickness, dermal-epidermal junction undulation and matrix-protein stimulation.
Beyond Surface Anti-Ageing: Four-Level Skin Regeneration
ARCHITECH-PRO Cream was modelled to affect multiple skin layers:
- Stratum corneum refinement
−7% reduction in thickness, improving surface texture - Epidermal strengthening
+6% increase in epidermal thickness - Dermal-epidermal cohesion
+68% increase in DEJ undulation - Matrix protein stimulation
Increases shown for collagen, laminin, elastin and fibrillin
The goal: stronger architecture, improved support, better bounce, and healthier cell signalling beneath the surface.
Ideal for Post-Procedure Regeneration and Skin Recovery
ARCHITECH-PRO Cream can be applied as a supportive post-procedure care step for:
- Fillers
- Mesotherapy
- Superficial peels
- Fractional laser
- Microneedling
- LED therapy
- Radiofrequency treatments
- HIFU (High-Intensity Focused Ultrasound)
It can be used immediately after most non-invasive procedures, and once healing is complete following deeper laser or chemical resurfacing.
For HIFU patients
When used twice daily after HIFU, internal assessments showed an amplified lifting response compared to HIFU alone — including improvements in sagging, contour definition and firmness.
Professional and At-Home Usage
FILLMED applies this formula across five structured protocols:
- In-clinic ultrasound reshaping
- Anti-sagging filler support routines
- Regenerative medi-spa facial treatments
- Lifting gua-sha facial massage
- Daily at-home matrix preservation
In the clinical environment, it may be used as part of combined protocols to maintain dermal support, refine texture and assist in skin comfort after energy-based or injectable treatments.
At home, it is positioned as a twice-daily pro-ageing treatment to help rebuild the skin’s underlying support network and improve visible signs associated with matrix loss.
The Sensory Experience
Formulated with 95% naturally-derived ingredients, the texture is crafted as a biomimetic lamellar emulsion — meaning it mirrors the skin’s own lipid structure for bio-affinity. It has a soft, cashmere feel, designed to melt into the skin and leave a non-greasy finish.
The twist-lock airless glass packaging supports formula protection, precise dosing, and reduced exposure to oxidation or contamination.
Where to Shop FILLMED in South Africa
Fillmed’s ARCHITECH-PRO Cream is priced at R2 800 for 50ml.
FILLMED products are available at these online stores:
For a full list of FILLMED stockists or to become a stockist, email info@gaactive.co.za or call +27 12 548 0725.
Follow FILLMED South Africa:
About the author
Rochelle is the founder and driving force behind the Aesthetic Appointment Journal. With a passion for the aesthetics and pro-ageing industry in South Africa, she has been in the aesthetic publishing industry since 2012, dedicated to creating a valuable platform for insights and knowledge, bridging the gap between patients and doctors - delivering reliable, medical-based information. Rochelle firmly believes in the power of a good skincare regimen, especially when started at home, and is committed to educating consumers about the myriad of treatments, procedures, and products available to them.