*Sponsored post: RocQ*
The aesthetics industry is constantly pushing boundaries with new treatments designed to work at a cellular level. One of the latest developments gaining interest from aesthetic practitioners and skincare enthusiasts is E-50, a skin and hair booster powered by salmon sperm-derived exosomes from PrimaCure in Korea, and distributed in South Africa by RocQ.
Exosomes may sound like a buzzword, but these microscopic vesicles are playing an increasingly important role in regenerative aesthetics. With a unique blend of polynucleotides (PNs), peptides, and growth factors, E-50 is designed to support the skin and scalp at a cellular level, helping to improve texture, tone, and overall appearance.
What Exactly Are Exosomes?
To understand E-50, it’s worth taking a closer look at exosomes themselves. Exosomes are nano-sized vesicles naturally produced by cells, acting as messengers that facilitate cell-to-cell communication.
Think of them as biological couriers that deliver instructions for repair and regeneration. In aesthetics, exosomes are being studied for their potential to encourage healing, reduce inflammation, and stimulate collagen and elastin production.
E-50 incorporates DNA-rich salmon milt extract, a natural source of polynucleotides, peptides, and nucleic acids. Salmon milt (the male reproductive extract, aka salmon sperm) has been researched for its role in wound healing and tissue support. When used in exosome form, it offers an innovative approach to promoting skin and hair health.
Why Salmon Milt?
Salmon-derived ingredients have become popular in advanced skincare for their regenerative potential. Unlike some synthetic alternatives, salmon milt is naturally 95% compatible with human skin and scalp, meaning it can integrate smoothly into cellular processes. It’s rich in nucleotides, the molecules that form the backbone of DNA and RNA, and can assist in supporting cellular function and repair.
In E-50, the salmon milt-derived exosomes act as bio-signals, encouraging the skin and hair follicles to perform more efficiently. With regular treatment, this may lead to improved elasticity, texture, and hair quality over time.
The Science Behind E-50
The polynucleotide-rich exosome complex in E-50 works in synergy with peptides and growth factors to deliver multi-layered support:
- Cell Repair and Renewal: Exosomes provide signals that may prompt fibroblasts and hair follicle cells to function optimally.
- Anti-Inflammatory Action: E-50 helps soothe skin and scalp that are prone to redness, sensitivity, or irritation.
- Boosted Collagen and Elastin: By supporting fibroblast activity, it may contribute to improved firmness and elasticity.
- Enhanced Barrier Function: The treatment supports the skin barrier, which helps defend against external stressors.
- Improved Radiance and Hair Density: Encourages more consistent cellular turnover, supporting visible skin and hair improvements.
Key Benefits of E-50 Skin Booster
- Firmer-feeling, more elastic skin
- A visible improvement in fine lines and texture
- Support for the skin’s natural healing processes
- May assist in repairing sun-related skin changes
- Helps calm sensitivity and visible redness
- Promotes a brighter, more balanced-looking complexion
E-50 can be used alongside in-clinic treatments such as microneedling, or energy-based devices. It offers a complementary approach for practitioners looking to support skin recovery and visible enhancement.
E-50 Professional Hair Treatment
The regenerative potential of E-50 isn’t limited to the skin. E-50 Hair Exosome Therapy is intended for patients experiencing thinning, weak, or brittle hair. The treatment delivers salmon-derived exosomes to the scalp, supporting follicle function and hair density.
This therapy may be used on its own or in combination with dermastamping or microneedling to help enhance absorption. Results can include stronger, shinier hair and less visible shedding — a promising option for patients considering non-invasive hair care treatments.
Watch out for the E-50 Shampoo for home use, which has just launched in South Africa!
What Does an E-50 Treatment Involve?
E-50 is applied topically after treatments like microneedling, which help improve penetration into the deeper layers of the skin or scalp. The procedure is minimally invasive (up to 0.5mm in depth) and usually involves little to no downtime, making it a suitable choice for patients seeking subtle but visible improvements.
A series of sessions, spaced a few weeks apart, is often recommended. Many patients begin to notice enhanced tone, texture, or hair vitality within a few treatments, although results vary.
Who Is It For?
E-50 may be suitable for a wide range of individuals, including:
- Those noticing early signs of ageing, such as fine lines or reduced elasticity
- Individuals with sun-exposed skin or uneven tone
- People with sensitive or redness-prone skin
- Patients experiencing mild to moderate hair thinning
- Anyone looking to support healthy skin and scalp function with an added regenerative boost
Because E-50 works at a cellular level, it is generally considered safe for most skin and scalp types.
E-50 Benefits
Rather than simply hydrating or plumping the skin, E-50 supports deeper regenerative activity. Its goal is to encourage the skin and scalp to maintain and repair themselves more effectively using natural biological signals.
This approach may be helpful for patients who want to support the skin’s foundational health, not just its surface appearance.
Pairing E-50 With Other Treatments
E-50 integrates well with many aesthetic procedures. It can be combined with:
- Microneedling – to support collagen stimulation
- Laser resurfacing – to encourage recovery and enhance results
- Chemical peels – to help soothe and balance the skin post-treatment
- Energy-based devices – to support firmer, healthier-looking skin
- PRP (Platelet-rich plasma) – for enhanced hair treatment outcomes
- Minoxidil – to complement topical hair regimens
For hair concerns, pairing E-50 with microneedling or dermastamping can enhance delivery and effectiveness by targeting the follicle more directly.
The At-Home Advantage
E-50 isn’t limited to in-clinic use. The range includes targeted at-home care options designed to complement professional treatments and support ongoing skin and scalp health.
The E-50 Exosome Popping Face Mask
Packed with salmon-derived exosomes, the E-50 face mask rejuvenates the skin by delivering growth factors and bioactive molecules. It boosts collagen production, calms inflammation, and supports natural healing for a radiant, revitalised complexion.
Formulated using PrimaCure’s proprietary Advanced Osmosome Technology, this advanced mask helps even out skin tone, reduce pigmentation, minimise sagging, and improve overall resilience. While ideal for post-treatment care, helping to soothe redness and replenish moisture, it’s also effective as a standalone product for regular home use.
Recommended frequency:
- After in-clinic procedures: apply immediately post-treatment
- For maintenance: 1–2 times per week, or as needed
E50 Exosome Hair Foamer (E50H At Home Hair Kit)
Specifically designed for the scalp, the E50 Exosome Hair Foamer delivers concentrated salmon-derived exosomes to help calm inflammation, hydrate the scalp, and support healthier-looking hair. The E50H AtHome Hair Kit, built for 28 days of daily treatment, complements in-clinic hair therapies to help maintain results between treatments.
Each kit includes two dry ampoules and two solvent ampoules, which are mixed and transferred into a foam applicator. Applied twice daily, the foam ensures targeted delivery while minimising waste and preventing spillage. The foam applicator should be refrigerated between uses to preserve potency.
E-50 Shampoo
The E-50-H Exosome Shampoo has now landed in South Africa, joining the E-50 homecare range. This daily-use scalp cleanser is designed to work in synergy with in-clinic hair protocols, helping to maintain scalp clarity, barrier function, and overall scalp resilience without disrupting its natural balance.
Formulated with multiple bioactive delivery systems, the shampoo uses vesicle-based and encapsulation technologies to stabilise marine extracts and active ingredients during the wash process. These actives are delivered directly to the scalp, creating a healthy foundation for hair while supporting post-procedure outcomes.
When and How to Use:
- Protocol use: Recommended after professional scalp treatments such as the K-Revive Hair Booster or E-50-H protocols
- Frequency: Suitable for daily or routine cleansing
- Method: Apply to wet hair, gently massage into the scalp, and rinse thoroughly. Repeat if required
Professional Integration Tip:
This shampoo is best used as part of an at-home maintenance plan and works optimally when paired with the E-50-H Homecare Daily Ampoule.
All E-50 at-home products are available through RocQ, the official distributor of PrimaCure E-50 Exosomes.
Final Thoughts
E-50 reflects the growing interest in regenerative aesthetics. Backed by science and powered by salmon milt-derived exosomes, this treatment supports the skin and scalp at a cellular level, helping to maintain resilience and vitality over time.
For patients, this may mean smoother-feeling skin and stronger-looking hair, all without the need for invasive intervention. For practitioners, E-50 offers a flexible addition to existing protocols, working well alongside other in-clinic treatments.
As research into regenerative medicine continues to evolve, E-50 provides one possible pathway in the broader conversation about how we care for our skin and hair, by supporting the body’s own ability to renew itself.
Distributed in South Africa by RocQ
Whether you’re a clinic looking to offer E-50 treatments or a patient wanting to find a provider near you, the team at RocQ can assist with product information, training guidance, and provider referrals.
🌐 Website: www.rocq.co.za
📞 Tel: +27 82 452 7392
📧 Email: info@rocq.co.za
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