*Sponsored post: GA Active Wholesalers* 

*Disclaimer: For medical regulatory reasons, we are unable to publish the brand name of the regenerative under-eye filler and skin-boosting injectable manufactured by Laboratoires Fillmed and distributed exclusively in South Africa by GA Active Wholesalers. Please consult your doctor for more information, or if you are a healthcare provider, contact GA Active Wholesalers directly to learn more info@gaactive.co.za / +27 12 548 0724 

The eye area is often the first place where signs of fatigue, ageing, and stress become visible, even when someone feels well-rested. Manufactured by Laboratoires Fillmed and distributed in South Africa by GA Active Wholesalers, this regenerative approach to the periorbital (eye) area reflects a shift in aesthetic medicine toward treatments that support both structure and skin function. This article explores how a new regenerative hyaluronic acid injectable can be used in this delicate region, focusing on visible outcomes, underlying skin quality, and clinical considerations.

What is the periorbital area, and why is it so complex?

The periorbital area refers to the region surrounding the eyes, including the tear trough (under-eye hollow), crow’s feet (fine lines at the outer corners of the eyes), and the upper cheek junction.

This area presents unique challenges:

The skin is very thin, meaning fine lines can appear more quickly
With age, the skin becomes thinner and more translucent, revealing underlying blood vessels and contributing to a bluish tone
Volume loss or fat pad changes can create hollowness and shadowing, leading to a tired appearance

Two key characteristics, whether congenital or acquired, often contribute to this:

Structural hollowness (tear trough)
Skin quality changes and fine lines

Together, these can create the impression of fatigue, even when a patient feels energised.

A regenerative approach to the eye area

Developed by Laboratoires Fillmed, this treatment category uses a regenerative hyaluronic acid injectable, designed specifically for the periorbital area, to address three key dimensions:

Replenish volume in the tear trough
Smooth superficial crow’s feet lines
Illuminate the skin by improving overall quality

Rather than dramatically altering appearance, the goal is to achieve predictable, natural-looking results with good tissue integration and minimal swelling.

How the technology works

The formulation, developed by Laboratoires Fillmed, is based on a combination of three types of hyaluronic acid, homogeneously incorporated into a single injectable:

Very long chains (>3.5 MDa)
Long chains (>1.5 MDa)
Free hyaluronic acid (>1.5 MDa)

This combination supports both mechanical correction (volume and smoothing) and biological activity within the skin.

The technology has been shown to:

Stimulate fibroblasts (cells responsible for collagen production)
Promote continuous collagen induction over approximately 180 days
Support dermal growth and improve skin integrity

This dual action contributes to both immediate visible improvement and longer-term skin regeneration.

Designed for a delicate anatomical area

The periorbital region requires a very specific balance of product characteristics.

Fillmed has designed this injectable with:

High cohesivity for controlled placement
Low viscosity for flexibility and smooth integration
Low swelling rate, reducing the risk of puffiness
Minimal Tyndall effect (bluish discolouration under the skin)

These properties support:

Predictable results
Even distribution within the tissue
A more natural appearance in a highly visible area

Clinical outcomes and patient response

Clinical data indicates:

Immediate visible results, with continued improvement over time
Results lasting up to 18 months, depending on treatment area and patient factors
High levels of patient satisfaction:
- ~92% immediate satisfaction
- ~82% still improved at 6 months
- ~85% reported being happier post-treatment

Additionally, the treatment demonstrates:

Low incidence of swelling or oedema
Minimal adverse effects consistent with expected post-injection responses

A tailored treatment approach is essential

The periorbital area cannot be approached with a one-size-fits-all method.

A structured assessment approach is typically used, taking into account:

Skin quality
Fat distribution
Muscle activity
Presence of fluid retention (oedema)

This allows for:

Accurate patient classification
Individualised treatment planning
Improved safety and outcomes

In some cases, combination approaches may be recommended. For example, improving skin quality alongside volume correction using an injectable skin booster also manufactured by Laboratoires Fillmed can enhance overall results. You can read more about this product here.

What to expect from treatment

Treatment is performed by a qualified medical practitioner following a detailed consultation.

The procedure typically:

Takes a short amount of time
Involves minimal downtime
May result in temporary redness, swelling, or bruising

Results develop progressively, with both immediate improvement and ongoing skin changes over time.

Final thoughts

Treating the eye area requires both precision and restraint. As aesthetic medicine continues to evolve, manufacturers such as Laboratoires Fillmed are focusing on treatments that support long-term skin health while maintaining natural expression.

For patients, this means looking less tired and more refreshed. For practitioners, it offers an approach that balances science, technique, and subtlety in one of the most delicate areas of the face.

*Disclaimer: For medical regulatory reasons, we are unable to publish the brand name of the regenerative under-eye filler and skin-boosting injectable manufactured by Laboratoires Fillmed and distributed exclusively in South Africa by GA Active Wholesalers. Please consult your doctor for more information, or if you are a healthcare provider, contact GA Active Wholesalers directly to learn more info@gaactive.co.za / +27 12 548 0724 